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Saturday, October 12, 2024

Thyroid Hormone Drives Curiosity and Exploratory Conduct, Research Finds


How you can Use Progesterone

Earlier than you think about using progesterone, it is very important perceive that it’s not a magic bullet, and that you simply get essentially the most profit by implementing a Bioenergetic weight loss program strategy that means that you can successfully burn glucose as your main gasoline with out backing up electrons in your mitochondria that reduces your vitality manufacturing. My new e-book, “Your Information to Mobile Well being: Unlocking the Science of Longevity and Pleasure” comes out very quickly and covers this course of in nice element.

Upon getting dialed in your weight loss program, an efficient technique that may assist counteract estrogen extra is to take transmucosal progesterone (i.e., utilized to your gums, not oral or transdermal), which is a pure estrogen antagonist. Progesterone is one among solely 4 hormones I consider many adults can profit from. (The opposite three are thyroid hormone T3, DHEA and pregnenolone.)

I don’t suggest transdermal progesterone, as your pores and skin expresses excessive ranges of 5-alpha reductase enzyme, which causes a good portion of the progesterone you are taking to be irreversibly transformed primarily into allopregnanolone and can’t be transformed again into progesterone.

Best Approach to Administer Progesterone

Please notice that when progesterone is used transmucosally in your gums as I counsel, the FDA believes that by some means converts it right into a drug and prohibits any firm from advising that on its label. Because of this firms like Well being Natura promotes their progesterone merchandise as “topical.”

Nevertheless, please perceive that it’s completely authorized for any doctor to suggest an off-label indication for a drug to their affected person. On this case, progesterone is a pure hormone and never a drug and may be very secure even in excessive doses. That is in contrast to artificial progesterone known as progestins which might be utilized by drug firms, however continuously, and incorrectly, referred.

Dr. Ray Peat has finished the seminal work in progesterone and doubtless was the world’s biggest skilled on progesterone. He wrote his Ph.D. on estrogen in 1982 and spent most of his skilled profession documenting the necessity to counteract the hazards of extra estrogen with low LA diets and transmucosal progesterone supplementation.

He decided that the majority solvents don’t dissolve progesterone properly and found that vitamin E is the very best solvent to optimally present progesterone in your tissue. Vitamin E additionally protects you towards harm from LA. You simply should be very cautious about which vitamin E you employ as most supplemental vitamin E available on the market is worse than nugatory and can trigger you hurt not profit.



It’s crucial to keep away from utilizing any artificial vitamin E (alpha tocopherol acetate — the acetate signifies that it is artificial). Pure vitamin E might be labeled “d alpha tocopherol.” That is the pure D isomer, which is what your physique can use.

There are additionally different vitamin E isomers, and also you need the whole spectrum of tocopherols and tocotrienols, particularly the beta, gamma, and delta varieties, within the efficient D isomer. For example of a really perfect vitamin E, you possibly can take a look at the label on our vitamin E in our retailer. You need to use any model that has an analogous label.

You should buy pharmaceutical grade bioidentical progesterone as Progesterone Powder, Bioidentical Micronized Powder, 10 grams for about $40 on many on-line shops like Amazon. That’s almost a 12 months’s provide, relying on the dose you select.

Nevertheless, you have to to buy some small stainless-steel measuring spoons as you have to a 1/64 tsp, which is 25 mg and a 1/32 tsp, which is 50 mg. A standard dose is often 25-50 mg and is taken half-hour earlier than mattress, because it has an anti-cortisol perform and can enhance GABA ranges for a superb evening’s sleep.

Sadly, this vendor continuously runs out of product, and if that’s the case, then you should use Merely Progesterone by Well being Natura. It’s premixed with vitamin E and MCT oil. Once more, whereas Well being Natura states that its product is for “topical use solely,” I like to recommend making use of it transmucosally, by rubbing it in your gums.

In case you are a menstruating girl, it is best to take the progesterone in the course of the luteal section or the final half of your cycle, which will be decided by beginning 10 days after the primary day of your interval and stopping the progesterone when your interval begins.

In case you are a male or non-menstruating girl, you possibly can take the progesterone daily for 4 to 6 months after which cycle off for one week. The perfect time of day to take progesterone is half-hour earlier than mattress because it has an anti-cortisol perform and can enhance GABA ranges for a superb evening’s sleep.

That is what I’ve been personally doing for over a 12 months with superb outcomes. I’m a doctor so don’t have any issues doing this. In the event you aren’t a doctor, it is best to seek the advice of one earlier than utilizing this remedy, as transmucosal progesterone remedy requires a physician’s prescription.

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